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From Atlanta: Approximately 85 miles NE 1 1/2 hrs.

I-85 North Go north to Gainesville Exit 113, which is Hwy 985/365.  Go 42 miles continuing on Hwy 365 to Hwy 384.  Turn left, go 16 miles to GA Hwy 75, turn right and go three miles into Helen.
   
GA 400 North Take 400 North until it ends. Continue ahead on GA Hwy 115.  Go 5 miles to the traffic light.  Turn right onto Hwy 115.  Go 13 miles to Cleveland.  At traffic light, turn left onto US 129 North.  Go to the next traffic light and turn right on Hwy 75 North.  9 miles to Helen.

From Greenville, SC: Approximately 120 miles.  2 hrs.

I-85 South Go south to Lavonia, GA.  Exit 173 (Hwy 17, Helen, Toccoa).  Travel west toward Toccoa and Clarkesville following Hwy 17 signs to Helen.

From Chattanooga, TN: Approximately 132 miles 3 hrs.

I-75 South Go south on I-75 to Dalton, GA.  Take Hwy 76 to Ellijay.  From Ellijay continue south on Hwy 52 to Dahlonega.  At Dahlonega, continue on 52/115 to Cleveland, GA.  At first traffic light in Cleveland, turn left onto US 129 North.  Go to the next traffic light and turn right on Hwy 75 North.  9 miles to Helen.

From Knoxville, TN: Approximately 166 miles – 4 hrs.

I-75 South I-75 South to Cleveland, TN.  Go east on Hwy 64 to junction of US 129 South.  Take 129 for about 30 miles to junction of 75 Alternate.  Continue on 75 Alternate for 9 miles to junction of 75 and then south one mile into Helen.

From Birmingham, AL Approximately 3 1/2 hrs.

I-20 East Take I-20 East to Atlanta, then I-285 By-Pass north toward Chattanooga.  Take GA 400 North to the end.  Continue ahead on GA Hwy 115.  Go 5 miles to the traffic light.  Turn right onto Hwy 115.  Go 13 miles to Cleveland.  At traffic light, turn left onto US 129 North.  Go to the next traffic light and turn right on Hwy 75 North.  9 miles to Helen.

From Florida:

I-75 to I-675 to I-285 to I-85 See above from Atlanta.